Militant
Formal Name： Mitoxantrone Hydrochloride Injection
English Name：Mitoxantrone Hydrochloride Injection （abbrievated MTZ）
Commercial Name： MILITANT
License Number：（96）Medical registered number No.X－84
Organic Functions：
Militant （MTZ） is one new compound anti-cancer medicine. its target enzyme is TOPOⅡ. MTZ's flat fragrant ring connected with basic group inset DNA double chain, then causing DNA basic group division, and single chain and double chain fissure.
As the national research observation：
surface adriacin an imported adriacin at the dense of 50μg／ml can react with DNA, national made adriacin at the dense of （100μg／ml） and  daunerubicin at the dense of （200μg／ml） only can react. But Militant can take action at lower dense of （25μg／ml） and kill tumor cells. On the other hand,MTZ has restrictive  function on RNA polyase, and can restrain the form of nucleic acid even dead cells. MTZ is one cell periodical non-peculiar medicine. It can combine with periodical cell DNA to release its anti-tumor function.
Indications：
Emergency leukemia, serious lymphoma, galactophore cancer, lung cancer and liver cancer, urinary ladder cancer, bone serious tumor, melanin tumor, prostate cancer, ovary cancer, esophagus cancer etc. Its new application to clinic home and abroad.：
Galactophore cancer：
This product is one most used medicine in foreign countries. it usually mixing used with VCR,CTX, and Changchun Ruibin etc. It has released out high reaction rate and fine tolerance. 
Emergency leukemia：
 Apart from the common adriacin application, this product has been listed as the first choice medicine by AML. High dose  （80㎎/㎡）this medicine's union usage with other medicine can fasten CR at 84％， which is obviously higher than daunerubicin. this medicine with MTZ, for those recurrence and difficult treatment gonorrhea patient, has an treatment efficiency at 85％， which is its peculiar priority. Now it has been the first treatment plan.
Serious lymph cancer：
In the treatment of serious lymph cancer, songlongBenz＋MTZ has more Cr than Cop, finer tolerance, and less side effects etc priorities.
Prostate cancer:
FDA has listed the MTZ as first choice medicine for later hormone resistant  prostate cancer.
Liver Caner：
Those cases of can not ablate liver cancer as recurrence or transference or before or during operation. injection in liver inner artery, adding iodized oil etc when treating. It has been widely applicated.
Ovary cancer：
Having obvious treatment function on disease cases of no cis diaminedichlorop treatment or treatment failure. glia cancer： partly treatment, united with operation and teletherapy, having carried on elementary research.
Intracavity application：
liver cancer, stomach cancer, ovary cancer, intestinum crassum cancer, etc intracavity  chemotherapy（IPC） and lung cancer.
Theurinary bladder cancer：
A：after TUR operation,MTZ20㎎ once per week， continuing 6－8 weeks， clysii washing for 2h， supporting treatment, preventing from recurrence.         B：.light theurinary bladder cancer（Pta-Pt1，1－3 grade） clysis washing  MTZ12㎎ once a week, six weeks later, once a month lasting 6-8 weeks, or MTZ20㎎ once a week, lasting 6-8 weeks.
Nasopharyngeal cancer：
MTZ12－14㎎/㎡ repeat per three weeks, or clysis treatment.
Bone serious tumor：
It can replace of common  chemotherapy adriacin.